Year 2 : Cancer Week

Lecture: Introduction to the Cancer Patient Pathway

1. Appreciate the implications of living with and beyond cancer
2. Understand the part research plays in the cancer patient pathway
3. Appreciate the role of the immune system in cancer
4. Understand the steps in the cancer patient pathway
5. Understand the concept of ‘red flags’ in cancer diagnosis and the cancer referral process
6. Revise the principles of cancer biology
7. Understand the general principles of cancer treatment: surgery, radiotherapy, chemotherapy, targeted and biological therapy.
8. Describe the purpose of the MDT and the role of the individuals within it
9. Develop insight into the patient experience of cancer

Overall aims

1. Revise the principles of cancer biology
2. Understand the steps in the cancer patient pathway
3. Understand the concept of red flags in cancer diagnosis and the cancer referral process
4. Describe the purpose of the MDT and the role of the individuals within it
5. Understand the general principles of cancer treatment: surgery, radiotherapy, chemotherapy, targeted and biological therapy.
6. Appreciate the role of the immune system in cancer
7. Understand the part research plays in the cancer patient pathway
8. Appreciate the implications of living with and beyond cancer
9. Develop insight into the patient experience of cancer

Lecture: Revision of Cancer Biology

Lecture: The GP- Presentation of Cancer in Primary Care

1. Understand GP involvement with cancer patients
2. Understand the NICE urgent referral system (2ww)
3. Understand the concept of ‘red flags’ in cancer diagnosis and the cancer referral process
4. Understand the ways that patients with cancer present to primary care

Lecture: The Multi-Disciplinary Team

1. Acknowledge some of the problems associated with MDT working
2. Understand the role of each professional within the MDT in the cancer patient pathway
3. Describe the ‘process’ of MDT working in an example speciality
4. Describe the multiple functions of the MDT
5. Define a multi-disciplinary team
6. Understand the role of the MDT in cancer management
7. Describe the purpose of the MDT and the role of the individuals within it

Lecture: Surgery

Lecture: Chemotherapy

Personalised and Stratified Medicine

Lecture: Targeted Therapy

1. To be able to describe the mechanisms of resistance to receptor tyrosine kinase antagonists (monoclonal antibodies and small molecule tyrosine kinase inhibitors)
2. Describe the mechanisms of action of small molecule tyrosine kinase inhibitors.
3. Understand the differences in naked therapeutic antibodies and antibody drug conjugates.
4. Describe the role of monoclonal antibodies in targeted therapies and using named examples the mechanism of action.
5. Gain an understanding of the aim of targeted therapy and to identify cancer targets.

Lecture: The Role of the Immune System in Cancer

1. Checkpoint inhibition and how this is being exploited to treat cancer
2. Cancer antigens and how they are used to vaccinate cancer
3. How cancer evades immune response
4. The use of monoclonal antibodies to treat cancer

Hematological Malignancies: A Historical Perspective

Lecture: The Role of Research in the Cancer Patient Pathway

1. The different phases of clinical trial and their purpose
2. The ethical considerations of trial enrolment
3. The importance of clinical trials in improving outcome in cancer patients

Lecture: Performing Medicine- Patient's Perspective

Lecture: Palliative Care

Lecture: Clinical Psychology

Cancer Case Studies

Decision Making in Biology and Medical Advice

Receptor Tyrosine Kinases and Cancer

Cancer Cell Death

Cancer Stem Cells

Cancer Proteomics

Hallmarks of Cancer

Haematological Cancers

Basic Principles of Cancer Therapy

Genome and Chromosome Abnormalities in Cancer

Cancer Therapy and Immunotherapy of Cancer